In the Lintz study, total resection of the ACL was performed in 17 out of 29 knees, while in the Ventura study total resection was performed in 17 out of 25 patients. Int J Curr Res Aca Rev 4(11):1824 http://www.ijcrar.com/abstractview.php?ID=228&vol=4-11-2016&SNo=3, Kim TH, Lee DH, Lee SH, Kim JM, Kim CW, Bin SI (2008) Arthroscopic treatment of mucoid hypertrophy of the anterior cruciate ligament. Keywords used for the Search were mucoid degeneration, anterior cruciate ligament and ACL. Mucoid degeneration of the ACL is suspected when an apparently thickened and ill-defined ligament with increased signal intensity on all sequences in MRI is identified in a patient with physically intact ligament and no obvious trauma history. Physical therapy typically begins 7-10 days after the procedure. Knee Surg Sports Traumatol Arthrosc 21(3):658663. The retrospective study by Kim et al. This is a characteristic appearance of ACL mucoid degeneration where the ACL is expanded and hyperintense but is still continuous with normal alignment. NCI CPTC Antibody Characterization Program. Mucoid degeneration of the anterior cruciate ligament (ACL) is a very rare cause of knee pain. See this image and copyright information in PMC. Cookies policy. Knee Surgery & Related Research Arch Orthop Trauma Surg. Management of mucoid degeneration of the anterior cruciate ligament: a systematic review. A positive Lachman test and a negative pivot shift were noted after surgery in all cases. Twenty knees (69%) had associated cartilaginous lesions and 19 (66%) had meniscal lesions. The minimum follow-up was 3 years. The cruciate ligament have mechanoreceptors, which are responsible to detect any change in position of the knee, direction, speed and tension. [Diagnosis and treatment of anterior cruciate ligament cysts]. Arthroscopic examination analyzed the ACL aspect and its associated lesions (meniscus, cartilage). What is Anterior Cruciate Ligament Mucoid Degeneration? We herein describe a case of PCL mucoid degeneration presented with secondary ACL . https://doi.org/10.1302/0301-620X.81B2.0810304, Article Sasaki R, Nagashima M, Takeshima K, Otani T, Okada Y, Aida S, Ishii K. J Int Med Res. Arthroscopic management of mucoid degeneration of anterior cruciate ligament. Mucoid degeneration of the ACL is suspected when an apparently thickened and ill-defined ligament with increased signal intensity on all sequences in MRI is identified in a patient with physically intact ligament and no obvious trauma history. 2012 Sep;46(5):561-5. doi: 10.4103/0019-5413.101037. These appearances must be differentiated from mucoid degeneration of the intact ACL. J Chin Med Assoc. 2021 Sep;50(9):1837-1843. doi: 10.1007/s00256-021-03750-7. Accessibility Several authors have identified this condition, described their experiences, and suggested their own guidelines for management. Its function is to stabilize the knee while bending and rotating; the ACL also keeps the knee from shifting out of place or moving anteriorly (toward the front) with pivoting activities. However, symptomatic instability was not common. The ligament is mainly responsible for restraining anterior translation of knee. 2004;182(5):12831287. HHS Vulnerability Disclosure, Help Conclusions Our study provides further evidence that arthroscopic total or partial excision of anterior cruciate ligament is a safe and effective treatment for mucoid degeneration of the anterior . The cause is not really known, but patients usually do not complain of instability. 3. Orthop Traumatol Surg Res. This site needs JavaScript to work properly. Mucoid degeneration of ACL. The patient presented with extension block of the knee. Mucoid degeneration of the ACL is a rare cause of knee pain.1-8) This lesion of the ACL was first reported by Kumar et al.3) in 1999. The pathogenesis remains controversial. https://www.physio-pedia.com/index.php?title=Anterior_Cruciate_Ligament_(ACL)_Mucoid_Degeneration&oldid=253974, Difficulty in climbing stairs, cross-leg sitting, squatting, Primary condition- Osteoarthritis, degenerative menisci, meniscal tear, Impingement of the soft tissue in the vicinity. in 1999 [ 1 ]. Pre-debridement arthroscopic view showing yellowish content in the anterior cruciate ligament. (B) Partial resection, MeSH Case report: No reconstruction was performed at the same time. The total number of patients with symptomatic instability was 18 out of 288 (6%). Check for errors and try again. Sweed, T., Mussa, M., El-Bakoury, A. et al. Anterior cruciate ligament mucoid degeneration: a review of the literature and management guidelines. proposed a different intervention called reduction plasty, whereby the hypertrophic ACL is reduced to normal size without excision of all mucoid substance [17]. 2008;24(6):642649. Eight studies reported postoperative instability. The authors declare that they have no competing interests. PubMedGoogle Scholar. A total of 313 knees in 292 patients were included in the nine studies. Methods: The minimum follow-up was 3 years. ACL debridement was partial in all studies except for those by Lintz et al. Postoperative pain relief ranged from 53.8 to 95%. 1. There was strong association with chondral lesions and meniscal tears. 2018 Apr;34(4):1054-1059. doi: 10.1016/j.arthro.2017.10.039. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Arthroscopic debridement of the ACL was the intervention in eight studies, whereas Morice et al. Before Online ahead of print. government site. The aim of this study was to detail the clinical, radiological, arthroscopic, and pathological findings of mucoid degeneration of the anterior cruciate ligament and report the clinical outcomes following arthroscopic treatment. Federal government websites often end in .gov or .mil. Ligaments are very tough, fibrous tissue structures. The .gov means its official. All patients with a preoperative limited ROM (100%, n=9) reported a return to a normal (subjective) ROM. Mucoid degenerated anterior cruciate ligament (ACL) managed by arthroscopic ACL reconstruction: A case series. Coronal T2 weighted fat suppressed fast spin echo image showed complex anterior cruciate ligament ganglion cyst arising from superior aspect of ligament. Knee Surg Sports Traumatol Arthrosc 19(8):13261333. https://doi.org/10.1186/s43019-021-00110-6, DOI: https://doi.org/10.1186/s43019-021-00110-6. Epub 2008 Dec 17. Manage cookies/Do not sell my data we use in the preference centre. Despite the low rate of complications in all studies, there was a high incidence of postoperative knee laxity, demonstrated by a positive Lachman test, in most studies. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. PubMed Central Physiopedia articles are best used to find the original sources of information (see the references list at the bottom of the article). 1173185. Online ahead of print. This site needs JavaScript to work properly. A 48-year-old-male patient presented with knee pain and limitation of motion. Mucoid degeneration (MD) of the anterior cruciate ligament (ACL) is a rare pathological entity that has been found in patients with pain and limited range of motion of the knee in association with a bulky ACL shown on magnetic resonance imaging (MRI). National Library of Medicine to 44% in the study of Cha et al. AJR Am J Roentgenol. 2009. The .gov means its official. Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) flowchart illustrating the selections of trials included in the systematic review. Epub 2011 Feb 18. Mucoid cystic degeneration of the cruciate ligament. 2010 Jun 1;96(4):400-6. Anterior cruciate ligament (ACL) mucoid degeneration, along with tears and anterior cruciate ligament ganglion cysts, is a relatively common cause of increased signal within the anterior cruciate ligament (ACL). Anterior cruciate ligament (ACL) mucoid degeneration, along with tears and anterior cruciate ligament ganglion cysts, is a relatively common cause of increased signal within the anterior cruciate ligament (ACL ). Most authors believe that partial ACL resection is the treatment of choice in symptomatic MD of the ACL. MeSH Ever since mucoid degeneration of the anterior cruciate ligament (MD-ACL) was named by Kumar et al. Disclaimer. [18] did not comment on an association between MDACL and chondral or meniscal lesions: after the exclusion of that report, the total number of patients with associated chondral lesions was 226 out of 275 patients (82%) and 190 patients had meniscal lesions (69%). Method. The .gov means its official. did not report on this. Complete resection of the ACL without ACL reconstruction is a reliable treatment for symptomatic cases of mucoid degenerated ACL. Fourteen knees (48%) had limited flexion, on average 97 degrees. Management of mucoid degeneration of the anterior cruciate ligament: a systematic review, https://doi.org/10.1186/s43019-021-00110-6, https://doi.org/10.1302/0301-620X.81B2.0810304, https://doi.org/10.1007/s00167-011-1433-0, https://doi.org/10.2214/ajr.182.5.1821283, https://doi.org/10.1007/s00167-012-1991-9, https://doi.org/10.1016/j.arthro.2003.11.030, https://doi.org/10.1016/j.jclinepi.2009.06.005, http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42018087782, https://doi.org/10.1046/j.1445-2197.2003.02748.x, http://journals.sagepub.com/doi/10.1177/2325967118786930, http://www.ijcrar.com/abstractview.php?ID=228&vol=4-11-2016&SNo=3, https://doi.org/10.1016/j.arthro.2008.02.004, https://doi.org/10.1016/j.jajs.2015.12.001, https://doi.org/10.4055/cios.2018.10.3.307, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/. -, Bergin D, Morrison WB, Carrino JA, Nallamshetty SN, Bartolozzi AR. For treatment of this, partial removing of bulky ACL is generally done, which causes weakness of the ACL. MRI - Interstitial ACL tear With Mild knee joint effusion ,No evidence of discontinuation of fibre Can Interstitial ACL tear heal without surgery Asked for Male, 22 Years 78 Views v Dr. Abhishek Kaushik Joint Replacement Surgeon | Delhi 1/1 people found this helpful Hi. Bilateral Symptomatic Mucoid Degeneration of the Anterior Cruciate Ligament with Anterior Knee Pain but No Limited Knee Flexion. Please enable it to take advantage of the complete set of features! Role of ultrasound-guided decompression in management of mucoid degeneration of the anterior cruciate ligament. Unable to process the form. Its signal is increased on all sequences. The presence of intraligamentous mucoid degeneration in the ACL is demonstrated as a source of knee pain without instability and partial ACL debridement did not preclude adequate knee stability. Its interstitial nature within the ACL structure contrasts with synovial cyst of the ACL. They reported that a biopsy indicated mucoid degeneration and a relief of symptoms could be obtained through arthroscopic partial resection of the ligament. 2. http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42018087782. They respond well to a judicious arthroscopic release of the ACL with notchplasty. Coronal proton density-weighted magnetic resonance imaging shows a thickening of the anterior cruciate ligament. Mucoid degeneration of ACL is a disease affecting ACL in which mucoid like substance (glycosaminoglycans) gets interspersed within the substance of ACL and as a result ACL gets thickened. 2011. 2022 Mar;50(3):3000605221084865. doi: 10.1177/03000605221084865. ACL (anterior cruciate ligament) mucoid degeneration means the lesion of the ACL. ACL mucoid degeneration is an uncommon pathological condition; the pathogenesis, prevalence, and association with other intra-articular knee structural damage are still poorly understood. MDACL is not uncommon, however, it is rarely symptomatic [4, 5]. Arch Orthop Trauma Surg. PubMed Skeletal Radiol. Orthop Traumatol Surg Res. government site. Dietary management and various treatments Scanning and diagnostic . The mean MINORS score was 9.5 out of 16 (412). PROSPERO. What you feel (symptoms) You feel heaviness in knee joint. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. eCollection 2021. Any discrepancy was resolved by the senior author. Anterior cruciate ligament mucoid degeneration: a review of the literature and management guidelines. Methodological quality of the studies was assessed using the Methodological Index for Non-Randomized Studies (MINORS) criteria [11] (Table1). Arthroscopy. For non-comparative studies, this consists of eight questions. It can cause pain and to a meniscal tear. maude adverse event report: genzyme biosurgery (ridgefield) synvisc one intra-articular hyaluronic acid This ranged from 90 to 95% in all studies, except in the report by Kim et al., where only 53.8% of patients (57/106) had complete pain relief after surgery. 2013;15(1). Symptomatic ACL mucoid degeneration in middle-age athletes. Hypothesis: However, young patients should be forewarned about the risk of instability, and an anterior cruciate ligament reconstruction could be necessary. FOIA Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. Most authors believe that partial ACL resection is the treatment of choice in symptomatic MD of the ACL. in 1999 [1]. https://doi.org/10.1046/j.1445-2197.2003.02748.x, Ekhtiari S, Horner NS, Bedi A, Ayeni OR, Khan M. The learning curve for the Latarjet procedure: a systematic review. Bergin D, Morrison WB, Carrino JA, Nallamshetty SN, Bartolozzi AR. Anterior cruciate ligament mucoid degeneration: a review of the literature and management guidelines. 2011 Aug;19(8):1326-33. doi: 10.1007/s00167-011-1433-0. At last follow-up, the mean visual analogue scale score, International Knee Documentation Committee score, and Tegner Lysholm Knee score improved (p < 0.01). Presentation Patients usually present with nonspecific posterior knee pain with restriction of flexion. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. Clin Orthop Surg 10(3):307314. Unauthorized use of these marks is strictly prohibited. 2001;17(9):E37. 287 (3): 912-921. Mucoid Degeneration of the Anterior Cruciate Ligament: Characterization of Natural History, Femoral Notch Width Index, and Patient Reported Outcome Measures. Patients and methods: sharing sensitive information, make sure youre on a federal Epub 2011 Feb 18. Two reviewers independently screened the titles and abstracts of the retrieved records for eligibility. 2011;19(3):408411. 2007;90(3):1923. This makes it difficult to relate the improvement of symptoms to ACL debridement. 2018 Sep;10(3):307-314. doi: 10.4055/cios.2018.10.3.307. Four studies reported only postoperative scores, which were comparable to those in other studies. The prevalence of MDACL on magnetic resonance imaging (MRI) ranges from 1.8 to 5.3% [4, 5]. Six studies reported using the pivot shift test; unsurprisingly, Lintz et al. Questions just answered: mucoid degeneration of acl physiotherapy. Arthroscopically ACL is intact but fibrillated, yellowish and hypertrophied,with interspersed yellowish mucinous material along the fibers, lack of synovial linning of the ACL. MUCOID DEGENERATION OF ACL - ARTHROSCOPIC TREATMENT 2,375 views Sep 15, 2019 23 Dislike Dr. Prateek Joshi- Ortho 1.02K subscribers Notice Age-restricted video (based on Community Guidelines). -, McIntyre J, Moelleken S, Tirman P. Mucoid degeneration of the anterior cruciate ligament mistaken for ligamentous tears. (A) Bulging of the hypertrophied anterior cruciate ligament. reported on the co-existence of mucoid degeneration and ganglia of the ACL. Arthroscopic diagnostic criteria [7] are (1) continuous ACL fibres, (2) increased ACL volume, (3) yellowish-coloured material expressed on palpation and (4) loss of ACL synovial lining. Unlike meniscal tears and chondral defects, the mucoid degeneration of the anterior cruciate ligament (ACL) is a rare cause of knee pain and there have been no case reports of mucoid degeneration of both the ACL and the posterior cruciate ligament (PCL). Mucoid degeneration, is the irreversible degeneration of the tissue with the infiltration of mucin(glycosaminoglycans) within the fibers[1][2]. Mucoid degeneration of the anterior cruciate ligament: MRI, clinical, intraoperative, and histological findings. have described the following MRI criteria [4]: (1) high signal intensity in the T1 and T2 sequences, (2) increased ACL volume and (3) continuous fibres of ACL shown in the T2 sequence. official website and that any information you provide is encrypted A systematic literature search in the databases MEDLINE, Embase, Google Scholar, Cochrane, ISI web of science and Scopus was performed through July 2020 by three independent reviewers. Introduction: Mucoid degeneration of the anterior cruciate ligament (ACL) is a little-known entity. Radiologic findings associated with mucoid degeneration of the anterior cruciate ligament. Epub 2018 Aug 22. Not really known: Mucoid degeneration of the ACL is seen most commonly in adults (35-55 years of age). Mucoid degeneration itself is described as a yellow or brown substance which can be either seen through the most anterior fibers of the ACL or found by probing between them [ 19, 35] (Fig. Hsu CJ, Wang SC, Fong YC, Huang CY, Chiang IP, Hsu HC. Noninfiltrating synovial cysts of the ACL were excluded. Google Scholar, Chudasama CH, Chudasama VC, Prabhakar MM (2012) Arthroscopic management of mucoid degeneration of anterior cruciate ligament. 2007;15 (1): 73-86. Bergin et al. Knee Surg Sports Traumatol Arthrosc. Instrumental treatment. Tissue biopsy was performed in 85% of patients (58 of 68) in the study of Cha et al. Google Scholar, Lintz F, Pujol N, Dejour D, Boisrenoult P, Beaufils P (2010) Anterior cruciate ligament mucoid degeneration: selecting the best treatment option. Keywords: Five studies demonstrated improved postoperative functional outcome scores compared to preoperative scores [6, 14, 16, 18, 19]. proposed reduction plasty, which is reduction of the ACL to normal volume without excision of all mucoid tissue. Unable to load your collection due to an error, Unable to load your delegates due to an error. -Delivered Pre-rehab care for breast cancer and thoracic cancer cases. (48.2% (14/29 patients) with symptomatic instability), which may be due to the large number of patients with total resection of the ACL (58.6% (17 out of 29 patients)) (Table 4). Postoperative ACL laxity is a common finding after ACL arthroscopic debridement, however, symptomatic instability is not. Morice et al. Morice et al. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. sharing sensitive information, make sure youre on a federal 2013 Jun 20;15:59. doi: 10.11604/pamj.2013.15.59.2534. The rate of simultaneous meniscectomy ranged from 13 to 44%. Bethesda, MD 20894, Web Policies Average postoperative International Knee Documentation Committee (IKDC) and Knee Injury and Osteoarthritis Outcome Scores (KOOS) were 71.2 (42.5 to 92.0) and 78.2 (26.4 to 99). Clipboard, Search History, and several other advanced features are temporarily unavailable. Anterior cruciate ligament mucoid degeneration: selecting the best treatment option. Anatomically, it is arranged in a crossed pattern with the Posterior Cruciate Ligament, forming an 'X', therefore, it is also known as cruciform ligament. ANZ J Surg 73(9):712716. Mucoid degeneration of the anterior cruciate ligament. 2006;69(9):44952. Loss to follow up was not mentioned in the other five studies [3, 6, 15, 17, 19]. The https:// ensures that you are connecting to the The visual analogue scale score, the International Knee Documentation Committee score, and the Tegner Lysholm Knee Score were collected preoperatively, postoperatively, and during the follow-up period. Please enable it to take advantage of the complete set of features! official website and that any information you provide is encrypted The appearance can mimic acute or chronic interstitial partial tears of the ACL. Ventura et al. Epub 2021 Mar 8. Every time when patient flexes the knee, thickened ACL impinges over posterior cruciate ligament (PCL) in the knee, causing knee pain and limited motion. Only nine studies met our inclusion criteria and they were all case series. Postoperative pain relief was reported in seven studies. Bethesda, MD 20894, Web Policies -, Hsu CJ, Wang SC, Fong YC, Huang CY, Chiang IP, Hsu HC. Sagittal proton density-weighted magnetic resonance image shows ill-defined anterior cruciate ligament with increased signal intensity and a celery stalk appearance of intact fibers. in 1999 [ 1 ]. Patients will . Ligaments hold our bones together and allow us to bend, twist, pivot and rapidly accelerate and decelerate and yet maintain the stability of our joints. MM and A performed the literature search, and data analysis. mucoid degeneration of acl mri. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. Histologically, there is a mucoid substance in connective tissue containing glycoproteins and mucoproteins [8]. Average postoperative differential laxity on the Telos device was 8.3 mm (5 to 13 mm). National Library of Medicine Anterior cruciate ligament; Arthroscopy; Knee; Mucoid degeneration. Mucoid degeneration of the anterior cruciate ligament (MD-ACL) was first characterized by Kumar et al. Mucoid degeneration of ACL Justamom21 Feb 17, 2023 7:27 AM Among other conditions - osteoarthritis, osteopenia, spondylolisthesis- an MRI report showed "severe mucoid degeneration of the ACL" in my left knee. Mucoid degeneration of both ACL and PCL. Anterior cruciate ligament reconstruction was required in only one young patient due to disabling instability. Coronal proton density-weighted magnetic resonance, Coronal proton density-weighted magnetic resonance imaging shows a thickening of the anterior cruciate, Sagittal proton density-weighted magnetic resonance, Sagittal proton density-weighted magnetic resonance image shows ill-defined anterior cruciate ligament with increased, Coronal T2 weighted fat suppressed fast spin echo image showed complex anterior cruciate, Pre-debridement arthroscopic view showing yellowish. In this review, the mean age of patients ranged from 31 to 78years; mean age was highest in the study of Kim et al. Knee Surg Sports Traumatol Arthrosc. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). An anterior cruciate ligament (ACL) mucoid degeneration, along with tears and anterior cruciate ligament ganglion cysts, is a relatively common cause of increased signal within the. Rajani AM, Shah UA, Mittal ARS, Gupta S, Garg R, Punamiya M. Knee Surg Relat Res. Seventeen females (67%) and eight males (33%) were included in the final analysis. 2004;182(5):12837. Patients with symptomatic MDACL commonly present with posterior knee pain and limitation of knee flexion or extension [2, 6]. Before This was lowest in the study of Cha et al. The primary intervention was arthroscopic ACL debridement in eight studies; this was combined with notchplasty in cases of impingement with the lateral wall of the notch in five studies [6, 14, 16,17,18] (Table 3). Cite this article. The clinical presentation is one of posterior pain with limited flexion. Imaging: Plain radiographs The purpose of this study was to investigate the outcome of management of MDACL by performing a systematic review of methods of treatment that have been reported. CAS 2022 Apr 11;31:67-71. doi: 10.1016/j.jor.2022.04.004. https://doi.org/10.1007/s002560100336, Narvekar A, Gajjar S (2004) Mucoid degeneration of the anterior cruciate ligament. 8600 Rockville Pike Furthermore, this raises the question as to whether the symptoms (pain and diminished range of movement) were solely due to MDACL and not secondary to other associated pathological conditions. and transmitted securely. Hide glossary Glossary. If you believe that this Physiopedia article is the primary source for the information you are refering to, you can use the button below to access a related citation statement. Other theories include Degenerative theory- MD could occur due to ageing.[3]. and Ventura et al. Level of evidence: Mucinous material within the substance of ACL produces pain and limited motion in the knee. The quality of methodology was excellent in one study, good in five studies, low in two studies and very low in one study (Tables 1 and 2). statement and The clinical presentation is one of posterior pain with limited flexion. Risk factors Predisposing factors include the following 1: aging The anterior cruciate ligament (ACL) is the most commonly injured of the major knee ligaments. Disclaimer. and transmitted securely. Does Femoral Intercondylar Notch Volume Differ in Anterior Cruciate Ligament-Injured Adult Patients Compared to the Uninjured? Anterior knee pain is the more common complaint. Radiology. 2010 Jun;96(4):400-6. doi: 10.1016/j.otsr.2010.02.008. Clinical Outcomes, Return to Sports, and Patient Satisfaction After Anterior Cruciate Ligament Reconstruction in Young and Middle-Aged Patients in an Asian Population-A 2-Year Follow-up Study. #radiologycpd #medicalimaging #imaging #radcme #rheumatology #arthritis #rheumatologist #orthopaedic #painphysician #physiotherapy #sportsmed #orthopaedic #mskmri. Mucoid degeneration (MD) of the anterior cruciate ligament (ACL) is a well-recognized pathology characterized by the degradation of collagen fibers and infiltration of a mucoidlike substance, [1,2 .
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